In this article, we attempt to delineate the relationship between bitcoin prices and global factors such as stock index, economic policy uncertainty, gold spot prices, implied volatility and crude oil prices in a time-frequency domain. We resort to wavelet-based analysis to capture the multiscale interactive behavior of bitcoin with global factors. We primarily show that bitcoin is insulated from global factors in the short run. However, the existence of a significant relationship of bitcoin with global factors cannot be denied in the medium to long run, which could be attributed to the endogenous and intertwined economic system. Among the global factors considered in the study, we find the impact of economic policy uncertainty and crude oil prices to be more prominent on bitcoin. Our study offers some interesting insights on multiscale sensitivity of bitcoin to global factors, which may be useful for investors for taking informed decisions.